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  1. Other namesClassic Creutzfeldt–Jakob disease
    SpecialtyNeurology
    SymptomsEarly: memory problems, behavioral changes, poor coordination, visual disturbances · Later: dementia, involuntary movements, blindness, weakness, coma
    ComplicationsAspiration pneumonia due to difficulty coughing
    How CJD Kills Your Brain
    How CJD Kills Your Brain
    Creutzfeldt-Jakob disease, or CJD, is a rare and fatal disorder that affects the brain. It causes rapid deterioration of mental functions and movement, leading to death within a year.
  1. Also known as: CJD, subacute spongiform encephalopathy
    Content medically reviewed by
    Dr. Karthikeya T Mverified specialist
    MD, Internal Medicine
    View full profile onLinkedIn logoLinkedIn
    An unusual neurologic disorder that leads to dementia followed by death. This is very rare condition.
    Condition Highlight
    Urgent medical attention is usually recommended by healthcare providers
    Is condition treatable?
    Treatments can help manage condition, no known cure
    Does diagnosis require lab test or imaging?
    Often requires lab test or imaging
    Time taken for recovery
    Can last several years or be lifelong
    How is condition transmitted?
    Transmitted through direct contact
    Condition Highlight
    Common for ages 60 and older
    Condition Highlight
    Family history may increase likelihood
    Condition Image
    Source: Focus Medica . For informational purposes only. Consult a medical professional for advice. Learn more
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  2. People also ask
    Creutzfeldt-Jakob (KROITS-felt YAH-kobe) disease, also known as CJD, is a rare brain disorder that leads to dementia. It belongs to a group of human and animal diseases known as prion disorders. Symptoms of Creutzfeldt-Jakob disease can be similar to those of Alzheimer's disease.
    See more... Creutzfeldt-Jakob disease (CJD) is a rapidly progressive, rare, transmissible, and universally fatal neurodegenerative condition caused by prion proteins. The condition has a long incubation period. CJD was first described in 1920 by Hans Creutzfeldt and later in 1921 and 1923 by Alfons Jakob.
    Creutzfeldt-Jakob disease is marked by changes in mental abilities. Symptoms get worse quickly, usually within several weeks to a few months. Early symptoms include: Personality changes. Memory loss. Impaired thinking. Blurry vision or blindness. Insomnia. Problems with coordination. Trouble speaking. Trouble swallowing. Sudden, jerky movements.
    There is no cure, but medications can relieve some of the symptoms. (See also Overview of Prion Diseases.) Creutzfeldt-Jakob disease (CJD) is a prion disease, which develops when a normal protein called cellular prion protein (PrPC) changes shape (misfolds) and becomes disease-causing prion.
  3. WEBJan 28, 2023 · Creutzfeldt-Jakob disease is a rare and fatal brain disorder that causes dementia. Learn about the symptoms, causes, risk factors and types of this prion disease, including variant CJD and iatrogenic CJD.

  4. Creutzfeldt-Jakob Disease | National Institute of Neurological ...

  5. Creutzfeldt Jakob Disease - StatPearls - NCBI Bookshelf

    WEBJan 30, 2024 · Creutzfeldt-Jakob disease (CJD) is a rare, fatal degenerative brain disorder caused by prion proteins. This condition belongs to a group of transmissible spongiform encephalopathies …